Pradeep (Sudeep) is a RJ in Bengaluru who has gone for an event to Hubli. On the return train journey he sees Tanu (Ramya) on the next seat looking sad and crying. Pradeep is a fun-loving guy and quick witted who tries to spread happiness wherever he goes and so tries to cheer her up.
On returning to Bengaluru, Pradeep joins work where he hosts an evening show called Mussanjemaatu. This is a popular show especially for depressed people and others who call to tell him their problems while he gives them advice and tries to make them look at life positively.
Meanwhile, Tanu has come to Bengaluru to stay with her friend Shweta (Anu Prabhakar). Tanu has just lost her mother and her drunkard father has brought a new wife. Shweta arranges a job for her as a receptionist and also introduces her to Pradeep’s show as she is herself a big fan. Pradeep bumps into Tanu one day on the road but she doesn’t remember him from the train journey. He keeps thinking of her and one day without him realizing it’s the same girl, Tanu calls him during his show and tells him about her problems in Hubli and why she left. Their relationship grows from here….